ALLOSTERIC TRANSITIONS OF SUPRAMOLECULAR SYSTEMS EXPLORED BY NETWORK MODELS: APPLICATION TO CHAPERONIN GROEL.

Allosteric transitions of supramolecular systems explored by network models: application to chaperonin GroEL.

Identification of pathways involved in the structural transitions of biomolecular systems is often complicated by the transient nature of the conformations visited across energy barriers and the multiplicity of paths accessible in the multidimensional energy landscape.This task becomes even more challenging in exploring B-12 1000MCG molecular syste

read more

Information is Power, Technology is Apropos and Food Security is a Must in Africa in the Post COVID-19 African States

This paper examines the impact of new Cooler media information technology on food security.It specifically determines the extent to which new media technologies such as Instagram, Twitter/X, LinkedIn, WhatsApp, and many more, are agents of development and underdevelopment in food security in Africa.Drawing on systematic qualitative method, thus stu

read more


Upregulation of the hypothalamo-neurohypophysial system and activation of vasopressin neurones attenuates hyperalgesia in a neuropathic pain model rat

Abstract Arginine vasopressin (AVP) is a hypothalamic neurosecretory hormone well known as an antidiuretic, and recently reported to be involved in pain modulation.The expression kinetics of AVP and its potential involvement in the descending pain modulation system (DPMS) in neuropathic pain (NP) remains unclear.We investigated AVP expression and i

read more